Radioactivity & Radiopharmaceuticals
A growing range of radioactive isotopes is currently being developed for diagnostic and therapeutic applications, posing problems in terms of labelling, dosimetry and measurement.
For trials involving radiopharmaceuticals, ABX-CRO takes care of site training in radiopharmaceutical techniques, all regulatory aspects (e.g. handling permits), estimation of human dosimetry (e.g. MIRD, OLINDA®, or 3D), and all applications to radiation safety authorities.
The navigation of your project through the ever-changing and most un-harmonised regulatory environment globally governing radiopharmaceutical trials, is a unique service of ABX-CRO, which has helped many sponsors to avoid time consuming errors in trial placement.
As a dedicated Molecular and Functional Imaging Core Lab, we provide you with comprehensive turn-key solutions covering all aspects of pre-clincal and clinical Imaging:
» Design of Imaging Studies or Sub-studies
» Site set-up, including
- Camera QA and certification
for study purposes
- Quantitative cross-calibration of PET,
SPECT & MRI scanners
» Multicentre PET, SPECT & MRI studies,
- Quantitative normalisation of
- Handling of data in proprietary formats
» Set-up of world-class image analysis panels for
- Semiquantitative (SUV) or
- Quantitative analysis, e.g.
- Kinetic modelling,
- Receptor occupancy studies
Dr. Marcus Bronzel