The reconstruction program is based on a combination of attenuation correction incorporated into the ordered-subset maximum-likelihood expectation maximization (OSEM) reconstruction6), and scatter correction by the transmission-dependent convolution subtraction (TDCS) originally proposed by Meikle et al7), with further optimization8,9). The TDCS technique has also been expanded to the 123I-isotope which has been validated in the clinical environment 10,11).
The QSPECT suiteTM can be applied to the projection data obtained from conventional SPECT systems fitted with different types of collimators (LEHR, LEGP etc). Projection data
|should be obtained by using parallel beam collimators, and should have been corrected for detector uniformity and center of rotation etc.
on the SPECT console. The use of fanbeam collimators is also possible, provided that the projection data have been converted to parallel beam equivalent, including the fanbeam-geometrical conversion and uniformity correction.
• OS: Windows XP (Service Pack 3:SP3), Windows Vista (service Pack2:SP2), Windows7
• CPU: >1GHz, x86 processor, 1GB memory (2GB for Windows Vista and Windows7)
• JAVA 1.6.25
• Disk area > 360 MB (excluding working space)
• Display XGA (1,024x768) or above
|6) Hudson H, Larkin R: Accelerated image reconstruction using ordered subsets of projection data. IEEE Trans Med Imaging 1994; 13: 601-609
7) Meikle S, et al.: A transmission-dependent method for scatter correction in SPECT. J Nucl Med 1994; 35 : 360-367
8) Narita Y, et al. Monte Carlo and experimental evaluation of accuracy and noise properties of two scatter correction methods for SPECT. Phys Med Biol 1996; 41: 2481-2496
9) Narita Y, et al: Monte Carlo evaluation of accuracy and noise properties of two scatter correction methods for 201Tl cardiac SPECT. IEEE Trans Nucl Sci. 1997; 44: 2465-2472
10) Iida H, et al. Effects of scatter and attenuation correction on quantitative assessment of regional cerebral blood flow with SPECT. J Nucl Med. Jan 1998; 39: 181-189
11) Kim KM, et al.: SPECT collimator dependency of scatter and validation of transmission dependent scatter compensation methodologies. IEEE Trans Nucl Sci 2001; 48: 689-696
12) Iida H , et al. Ann Nucl Med 2012, in press